Browsing by Author "Chindemi, A."
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Item Felbamate efficacy and tolerability in patients with refractory epilepsy: An open add-on multicentric study.(1997) Perniola, T.; Margari, L.; Spina, A.; Chindemi, A.; Bello, A.; De Iaco, M.G.; De Giacomo, A.; Galluzzi, R.; Marzocco, P.L.; Piscitelli, L.A multicenter study that evaluated felbamate efficacy and tolerability in 19 patients with refractory epilepsy was performed. One patient (5,3%) became seizure-free during felbamate treatment, 11 patients (57,9%) achieved a seizure reduction of 50% or more, 6 patients (31,6%) evidenced an unchanged seizure frequency and 1 patient (5,3%) had increase in seizure frequency. Of the 7 patients (36,8%) who had a diagnosis of Lennox-Gastaut syndrome, 5 (71,4%) had >50% reduction in seizure frequency, 1 (14,2%) had unchanged seizure frequency and 1 (14,2%) had an increase in seizure frequency.