Browsing by Author "Bockarie, Y."
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Item Incidence, causes and correlates of maternal near‐miss morbidity: a multi‐centre cross‐sectional study(BJOG: An International Journal of Obstetrics and Gynaecology, 2019-05) Oppong, S.A.; Bakari, A.; Bell, A.J.; Bockarie, Y.; Adu, J.A.; Turpin, C.A.; Obed, S.A.; Adanu, R.M.K.; Moyer, C.A.To explore the incidence and factors associated with maternal near‐miss. Cross‐sectional study with an embedded case‐control study. Three tertiary referral hospitals in southern Ghana. All women admitted to study facilities with pregnancy‐related complications or for birth. An adapted version of the WHO Maternal Near Miss Screening Tool was used to identify maternal near‐miss cases. These were compared with unmatched controls (uncomplicated deliveries) in a ratio of 1:2. Incidence of maternal near‐miss, maternal near‐miss‐maternal mortality ratio, and cause of and factors associated with maternal near‐miss. Out of 8,433 live births, 288 maternal near‐miss cases and 62 maternal deaths were identified. 454 healthy controls were recruited for comparison. Maternal near‐miss and maternal death incidence ratios were 34.2 (95% CI:30.2 ‐ 38.1) and 7.4 (95% CI:5.5 ‐ 9.2) per 1000 live births respectively with a maternal near‐miss‐mortality ratio of 4.6:1. Cause of near‐miss was preeclampsia/eclampsia (41.0%), haemorrhage (12.2%), maternal sepsis (11.1%), and ruptured uterus (4.2%). Major factor associated with maternal near‐miss was maternal fever within the seven days before birth (OR:5.95 95%CI:3.754 ‐ 9.424). Spontaneous onset of labor was protective against near miss OR:0.09 95% CI: 0.057 ‐ 0.141) For every maternal death, there were nearly five maternal near‐misses. Women having a fever in the seven days prior to delivery were six times more likely to experience a near‐miss than women not having fever. This article is protected by copyright. All rights reserved.Item Neonatal near-misses in Ghana: a prospective, observational, multi-center study(BMC Pediatrics, 2019-12-23) Oppong, S.A.; Bakari, A.; Bell, A.J.; Bockarie, Y.; Wobil, P.; Plange-Rhule, G.; Goka, B.Q.; Engmann, C.M.; Adanu, R.M.; Moyer, C.A.Background: For every newborn who dies within the first month, as many as eight more suffer life-threatening complications but survive (termed ‘neonatal near-misses’ (NNM)). However, there is no universally agreed-upon definition or assessment tool for NNM. This study sought to describe the development of the Neonatal Near-Miss Assessment Tool (NNMAT) for low-resource settings, as well as findings when implemented in Ghana. Methods: This prospective, observational study was conducted at two tertiary care hospitals in southern Ghana from April – July 2015. Newborns with evidence of complications and those admitted to the NICUs were screened for inclusion using the NNMAT. Incidence of suspected NNM at enrollment and confirmed near-miss (surviving to 28 days) was determined and compared against institutional neonatal mortality rates. Suspected NNM cases were compared with newborns not classified as a suspected near-miss, and all were followed to 28 days to determine odds of survival. Confirmed near-misses were those identified as suspected near-misses at enrollment who survived to 28 days. The main outcome measures were incidence of NNM, NNM:mortality ratio, and factors associated with NNM classification. Results: Out of 394 newborns with complications, 341 (86.5%) were initially classified as suspected near-misses at enrollment using the NNMAT, with 53 (13.4%) being classified as a non-near-miss. At 28-day follow-up, 68 (17%) had died, 52 (13%) were classified as a non-near-miss, and 274 were considered confirmed near-misses. Those newborns with complications who were classified as suspected near-misses using the NNMAT at enrollment had 12 times the odds of dying before 28 days than those classified as non-near-misses. While most confirmed near-misses qualified as NNM via intervention-based criteria, nearly two-thirds qualified based on two or more of the four NNMAT categories. When disaggregated, the most predictive elements of the NNMAT were gestational age < 33 weeks, neurologic dysfunction, respiratory dysfunction, and hemoglobin < 10 gd/dl. The ratio of near-misses to deaths was 0.55: 1, yet this varied across the study sites. Conclusions: This research suggests that the NNMAT is an effective tool for assessing neonatal near-misses in lowresource settings. We believe this approach has significant systems-level, continuous quality improvement, clinical and policy-level implications.Item "We call them miracle babies": How health care providers understand neonatal near-misses at three teaching hospitals in Ghana(PLoS ONE, 2018-05) Bell, A.J.; Wynn, L.V.; Bakari, A.; Oppong, S.A.; Youngblood, J.; Arku, Z.; Bockarie, Y.; Adu, J.; Wobil, P.; Plange-Rhule, G.; Goka, B.; Adanu, R.M.; Moyer, C.A.Neonatal mortality is a significant problem in many low-resource countries, yet for every death there are many more newborns who suffer a life-threatening complication but survive. These "near-misses" are not well defined, nor are they well understood. This study sought to explore how health care providers at three tertiary care centers in Ghana (each with neonatal intensive care units (NICUs)) understand the term "near-miss." Eighteen providers from the NICUs at three teaching hospitals in Ghana (Korle Bu Teaching Hospital in Accra, Komfo Anokye Teaching Hospital in Kumasi, and Cape Coast Teaching Hospital in Cape Coast) were interviewed in depth regarding their perceptions of neonatal morbidity, mortality, and survival. Near the end of the interview, they were specifically asked what they understood the term "near-miss" to mean. Participants included nurses and physicians at various levels and with varying years of practice (mean years of practice = 9.33, mean years in NICU = 3.66). Results indicate that the concept of "near-misses" is not universally understood, and providers differ on whether a baby is a near-miss or not. Providers disagreed on the utility of a near-miss classification for clinical practice, with some suggesting it would be helpful to draw their attention to those at highest risk of dying, with others suggesting that the acuity of illness in a NICU means any baby could become a 'near-miss' at any moment. Further efforts are needed to standardize the definitions of neonatal near-misses, including developing criteria that are able to be assessed in a low-resource setting. In addition, further research is warranted to determine the practical implications of using a near miss tool in the process of providing care in a resource-limited setting and whether it might be best reserved as a retrospective indicator of overall quality of care provided.