Abstract:
The global effort to eradicate malaria requires a drastic measure to terminate relapse from
hypnozoites as well as transmission via gametocytes in malaria-endemic areas. Primaquine
has been recommended for the treatment of P. falciparum gametocytes and P. vivax hypnozoites,
however, its implementation is challenged by the high prevalence of G6PD deficient
(G6PDd) genotypes in malaria endemic countries. The objective of this study was to profile
G6PDd genotypic variants and correlate them with malaria prevalence in Ghana.