Leke, R.G.F.Ndansi, R.Southerland, N.J.Quakyi, I.A.Graves, P.M.Drake, J.C.Allegra, C.J.2013-06-212017-10-162013-06-212017-10-161992Leke, R. G. F., Ndansi, R., Southerland, N. J., Quakyi, I. A., & Taylor, D. W. (1992). Identification of anti-plasmodium falciparum antibodies in human breast milk. Scandinavian Journal of Immunology, Supplement, 36(11), 17-22.03016323http://197.255.68.203/handle/123456789/3797Malarial infections are rarely observed in neonates. It has been postulated that some immunity may be passively transferred during nursing, but anti-malarial antibodies (Abs) have not been detected in human milk. In this study milk samples collected 2-14 days after parturition from women at the Central Maternity Hospital, Yaounde were evaluated for total IgG and IgA antibody levels by radial diffusion, protein composition by SDS-PAGE, anti-malarial antibodies using an isotype-specific immunofluorescence assay, and the ability to immunoprecipitate Plasmodium falciparum antigens metabolically labelled with 35S-methionine. Results showed that anti-P. falciparum antibodies were present in breast milk, and that paired milk and serum samples from individual women contained Abs that recognized similar malarial antigens.enEMTREE drug terms: immunoglobulin A; immunoglobulin G; immunoglobulin M; parasite antibody; protozoon antibodyEMTREE medical terms: adult; breast milk; clinical article; conference paper; controlled study; female; human; immunofluorescence; Plasmodium falciparum; priority journal; serum; adolescent; animal; article; immunologyMeSH: Adolescent; Adult; Animal; Antibodies, Protozoan; Female; Human; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Milk, Human; Plasmodium falciparum; Support, Non-U.S. Gov't; Support, U.S. Gov't, Non-P.H.S.Article