Mensah, G.I.Vicar, E.K.Acquah, S.E.K.et al.2023-06-302023-06-302023https://doi.org/10.1155/2023/3727265http://ugspace.ug.edu.gh:8080/handle/123456789/39458Research AritcleUrinary tract infection (UTI) is frequently encountered during pregnancy and is associated with adverse maternal, fetal, and neonatal efects. However, very little information is available on the prevalence of UTI among pregnant women in the northern part of Ghana, a region with a high birth rate. Tis study employed a cross-sectional analysis of the prevalence, antimicrobial profle, and risk factors associated with UTI in 560 pregnant women attending primary care for antenatal check-ups. Sociodemographic obstetrical history and personal hygiene information were obtained using a well-structured questionnaire. Afterward, clean catch mid-stream urine samples were collected from all participants and subjected to routine microscopy examination and culture. Of 560 pregnant women, 223 cases (39.8%) were positive for UTI. Tere was a statistically signifcant association between sociodemographic, obstetric, and personal hygiene variables and UTI (p < 0.0001). Escherichia coli (27.8%) was the commonest bacterial isolate followed by CoNS (13.5%) and Proteus species (12.6%). Tese isolates exhibited greater resistance to ampicillin (70.1–97.3%) and cotrimoxazole (48.1–89.7%) but were fairly susceptible to gentamycin and ciprofoxacin. Gram-negative resistance to meropenem was up to 25.0%, and Gram positives resistance to cefoxitin and vancomycin was up to 33.3% and 71.4% respectively. Te current fndings extend our knowledge of the high frequency of UTIs and associated risk factors in pregnant women with E. Coli being the predominant and usual isolate. Variation existed in the resistance pattern of isolates to various drugs, underscoring the need to perform urine culture and susceptibility before treatment.enUrinary tract infectionNorthern RegionGhanaPregnant WomenAntenatal CareArticle