Anaman, P.D.Ahmed, I.A.Suleman, A.Dzakah, G.A.2024-08-022024-08-022023DOI: 10.1177/22785337231162740https://ugspace.ug.edu.gh/handle/123456789/42220Research ArticleIn line with the natural resource-based view, this paper explores sustainable business practices (SBPs) of Ghanaian micro, small, and medium enterprises (MSMEs). Qualitatively, the study interviewed eight MSME operators and middle-level managers purposefully assess their use of SBPs and how it affects their businesses. The collected data were edited, coded, and grouped under themes based on the Braun and Clarke thematic framework. The study identified holistic environmental management, eco-preneurship, and regenerative practices as the environmental stewardship drivers among Ghanaian MSMEs. Also, integrated vision and strategy, process efficiency and resource optimization, and risk profiling drive process excellence. Finally, sustainability-focused leadership, internal advocates and change agents, and ongoing education and awareness as drivers for sustainability-oriented culture. The business practices of organizations have continually impacted the immediate environment within which they operate. Consequently, there is a clarion call for businesses to engage in SBPs to mitigate the effect of their operations on the environment. The study brings to bear the SBPs Ghanaian MSMEs are engaged in and how they affect their operations and survival, especially in this era of sustainability.enSustainable business practicesenvironmental concernsthematic analysisArticle