Browsing by Author "Adokoh, C.K."
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Item Innovations and modifcations of current extraction methods and techniques of citrus essential oils: a review(Discover Applied Sciences, 2024) Brah, A.S.; Obuah, C.; Adokoh, C.K.The genus Citrus of the Rutaceae family remains one of the benefcial fruit crops that produce high quantities of essential oils that have pharmaceutical, biological, and food preservative applications. Despite the numerous benefts of citrus essential oils (CEOs), there is a major challenge in choosing the most efcient extraction method(s) for large-scale pro duction of quality CEOs to meet industrial, research, and domestic demands. This review provides a general overview of the listed citrus species, the chemical composition of their essential oils, medicinal uses, and the major methods of extraction of citrus essential oils from 10 selected citrus species. A meticulous, in-depth review of the various methods of CEOs extraction has been provided, along with their advantages, limitations, and novel modifcations. This compre hensive literature review expounded on the current extraction methods for citrus essential oils and the various modi fcations developed to reduce the extraction time, excessive energy consumption, CO2 production, and quality, as well as to improve the extraction yield.Item Toxicity and therapeutic applications of citrus essential oils (CEOs): a review(International Journal of Food Properties, 2023) Brah, A.S.; Armah, F.A.; Obuah, C.; Akwetey, S.A.; Adokoh, C.K.Citrus essential oil (CEO) is obtained from the fruit of Genus Citrus, a flowering plant shrub in the family of the Rutaceae (Eremocitrus or Microcitrus) and extensively used in food, chemical industry, and traditional medicinal treatment owing to its pleasant aroma, antioxidant, and antiseptic properties. This review presents a botanical description, distribution, traditional uses, chemical composition, bioactive components, and the therapeu tic uses as well as toxicological effects of the CEO. The objective was achieved via a comprehensive literature search of electronic databases such as Science Direct, PubMed, Web of Science, Wiley, ACS, Springer, Taylor and Francis, Google Scholar, SCOPUS, conference proceedings, thesis, and books until 2022 for publications. Citrus essential oils and their constituents are extracted and isolated either from the fruit peels, seeds, leaves, or flowers of the citrus plants. A comparative study of the sources of CEO confirmed its origin, ethnopharmacological and therapeutic uses. Over 2000 secondary metabolites have been isolated, with the main active constituents: being terpenes, monoterpenes, sesquiterpenes, and diterpenes. A comprehensive literature review revealed vast therapeutic benefits of CEO. Incomplete data report on in vitro and in vivo trials especially, on dosage, positive and negative control groups, intervention time, toxicity studies, phytochemical profiling, and clinical trials seem to be a knowledge gap.