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Sickle cell trait, hemoglobin C trait, and Burkitt's lymphoma.

Show simple item record Nkrumah, F.K. Perkins, I.V. 2013-06-20T13:17:15Z 2017-10-16T13:01:55Z 2013-06-20T13:17:15Z 2017-10-16T13:01:55Z 1976
dc.identifier.citation Nkrumah, F. K., & Perkins, I. V. (1976). Sickle cell trait, hemoglobin C trait, and Burkitt's lymphoma. American Journal of Tropical Medicine and Hygiene, 25(4), 633-636. en_US
dc.description.abstract In a controlled study in Ghana, the hemoglobin electrophoretic pattern in 112 patients with Burkitt's lymphoma was compared to that of their nearest neighbor controls of the same age, sex, and tribe, as well as their sibling controls. Analysis of the data obtained did not show any statistically significant protective advantage for sickle cell trait against Burkitt's lymphoma. Hemoglobin C trait appeared to offer a slight protective advantage (p<0.1), but this did not reach statistical significance. These results do not disprove the malaria co factor hypothesis in the etiology of Burkitt's lymphoma, but deprive it of an additional indirect evidence in its favor. en_US
dc.language.iso en en_US
dc.publisher American Journal of Tropical Medicine and Hygiene en_US
dc.title Sickle cell trait, hemoglobin C trait, and Burkitt's lymphoma. en_US
dc.type Article en_US

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  • Virology Department [138]
    Most research activities involve the use of molecular methods such as regular PCR (PCR), quantitative PCR (Q-PCR), genomic sequence and analysis using different software, genetic engineering, probe hybridization techniques, biological and molecular cloning, evaluation of immune markers for laboratory diagnosis of infections, serological assays involving the use of rapid tests, ELISA-based evaluations and immunofluorescent assay techniques.

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