dc.contributor.author |
Akpalu, A.K. |
|
dc.contributor.author |
Nyame, P.K. |
|
dc.date.accessioned |
2019-10-09T16:42:25Z |
|
dc.date.available |
2019-10-09T16:42:25Z |
|
dc.date.issued |
2009-12 |
|
dc.identifier.uri |
http://www.ghanamedj.org/articles/December2009/Final%20modifiable%20risk%20factors%20for%20cerebrovascular%20diseas.pdf |
|
dc.identifier.uri |
http://ugspace.ug.edu.gh/handle/123456789/32573 |
|
dc.description |
Jornal Article |
en_US |
dc.description.abstract |
Background: Stroke is an increasing problem in Ghana
and the West African sub-region. New and modifiable
risk factors for stroke have gained prominence in
the last decade but have not been adequately researched
in West Africa.
Methods: This was a case-control study with plasma
Homocysteine (Hcy) as an independent risk factor for
stroke. 80 consecutive stroke patients with 80 age-sex
matched controls were venesected in the fasting state
for assay of Hcy and other biochemical parameters.
Results: Mean Hcy level in stroke cases of 40.7 +
9.5μmol/l was significantly higher than 16.8 +
10.6μmol/l in controls [p<0.0001]. There was a significant
association of hyperHcy with stroke [χ2;
p<0.0001]. OR of stroke calculated for quartiles of
Hcy, demonstrated an increase in OR of 1.37 (25th percentile)
to an OR of 3.80 (75th percentile).
Conclusions: Hcy was elevated in patients with stroke
and should be considered as a modifiable risk factor for
stroke in Ghanaian adults. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Ghana Medical Journal |
en_US |
dc.relation.ispartofseries |
43;4 |
|
dc.subject |
Stroke |
en_US |
dc.subject |
Homocysteine |
en_US |
dc.subject |
Hyperhomocysteinemia |
en_US |
dc.subject |
Infarction |
en_US |
dc.subject |
Haemorrhage |
en_US |
dc.subject |
Ghana |
en_US |
dc.title |
Plasma Homocysteine as a Risk Factor for Strokes in Ghanaian Adults |
en_US |
dc.type |
Article |
en_US |