When is "malaria" malaria? The different burdens of malaria infection, malaria disease, and malaria-like illnesses.

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dc.contributor.author Koram, K.A.
dc.contributor.author Molyneux, M.E.
dc.date.accessioned 2013-06-26T20:02:05Z
dc.date.accessioned 2017-10-16T13:01:35Z
dc.date.available 2013-06-26T20:02:05Z
dc.date.available 2017-10-16T13:01:35Z
dc.date.issued 2007-12
dc.identifier.citation Koram, K. A., & Molyneux, M. E. (2007). When is "malaria" malaria? The different burdens of malaria infection, malaria disease, and malaria-like illnesses. The American Journal of Tropical Medicine and Hygiene, 77(6 Suppl), 1-5 en_US
dc.identifier.issn 00029637
dc.identifier.uri http://197.255.68.203/handle/123456789/4225
dc.description.abstract In this review we discuss the different meanings of the term 'malaria' and urge writers and readers to distinguish accurately between them. The distinction is important in clinical practice, clinical trials, epidemiology, and the evaluation of control programs. Both over- and under-diagnosis of malaria as the cause of a disease episode are inevitable; over-diagnosis is common in high-transmission areas and underdiagnosis is common in areas with little or no transmission. Parasite density thresholds, attributable fractions, and clinical algorithms have played important but only partial roles in strengthening diagnosis. Methods by which malaria infection could be confidently identified as the cause, rather than an irrelevant accompaniment, of an illness, are important targets for research. One such 'signature' is a distinctive retinopathy that occurs in severe malaria and not in clinically similar diseases. Other indicators of a malarial etiology of clinical disease are needed to strengthen clinical and scientific approaches to the control of malaria. Copyright © 2007 by The American Society of Tropical Medicine and Hygiene. en_US
dc.language.iso en en_US
dc.subject EMTREE medical terms: animal; cost of illness; human; malaria; parasitology; Plasmodium; review en_US
dc.title When is "malaria" malaria? The different burdens of malaria infection, malaria disease, and malaria-like illnesses. en_US
dc.type Article en_US


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  • Epidemiology Department [254]
    The Epidemiology Department contributes to the mission of the institute through basic and applied epidemiological research on, but not limited to, malaria and other diseases of public health importance. It is also home to the Social Science Unit of the Institute, including the Health Support Centre for HIV/AIDS and other communicable and noncommunicable health problems.

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