A tuberculin skin test survey among Ghanaian school children.

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dc.contributor.author Addo, K.K.
dc.contributor.author Van, D.H.S.
dc.contributor.author Mensah, G. I.
dc.contributor.author Hesse, A.
dc.contributor.author Bonsu, C.
dc.contributor.author Koram, K.A.
dc.contributor.author Afutu, F.K.
dc.contributor.author Bonsu, F. A
dc.date.accessioned 2013-06-26T13:30:33Z
dc.date.accessioned 2017-10-16T12:59:20Z
dc.date.available 2013-06-26T13:30:33Z
dc.date.available 2017-10-16T12:59:20Z
dc.date.issued 2010
dc.identifier.citation 4. Addo, K. K., Van Den Hof, S., Mensah, G. I., Hesse, A., Bonsu, C., Koram, K. A., Bonsu, F. A. (2010). A tuberculin skin test survey among Ghanaian school children. BMC Public Health, 10 en_US
dc.identifier.issn 14712458
dc.identifier.uri http://197.255.68.203/handle/123456789/4172
dc.description.abstract Background. Ghana has not conducted a national tuberculin survey or tuberculosis prevalence survey since the establishment of the National Tuberculosis Control Programme. The primary objective of this study was therefore to determine the prevalence of tuberculin skin sensitivity in Ghanaian school children aged 6-10 years in 8 out of 10 regions of Ghana between 2004 and 2006. Methods. Tuberculin survey was conducted in 179 primary schools from 21 districts in 8 regions. Schools were purposively selected so as to reflect the proportion of affluent private and free tuition public schools as well as the proportion of small and large schools. Results. Of the 24,778 children registered for the survey, 23,600 (95.2%) were tested of which 21,861 (92.6%) were available for reading. The age distribution showed an increase in numbers of children towards older age: 11% of the children were 6 years and 25%, 10 years. Females were 52.5% and males 47.5%. The proportion of girls was higher in all age groups (range 51.4% to 54.0%, p < 0.001). BCG scar was visible in 89.3% of the children. The percentage of children with a BCG scar differed by district and by age. The percentage of children with a BCG scar decreased with increasing age in all districts, reflecting increasing BCG vaccination coverage in Ghana in the last ten years. The risk of tuberculosis infection was low in the northern savannah zones compared to the southern coastal zones. Using a cut-off of 15 mm, the prevalence of infection ranged from 0.0% to 5.4% and the Annual Risks of Tuberculosis Infection 0.0% to 0.6%. There was an increase in the proportion of infected children after the age of 7 years. Children attending low and middle-class schools had a higher risk of infection than children attending upper-class schools. Conclusion. Tuberculosis infection is still a public health problem in Ghana and to monitor the trend, the survey needs to be repeated at 5 years interval. © 2010 Addo et al; licensee BioMed Central Ltd. en_US
dc.language.iso en en_US
dc.subject EMTREE drug terms: BCG vaccine EMTREE medical terms: age distribution; article; child; female; Ghana; health survey; human; male; prevalence; risk; sex ratio; tuberculin test; tuberculosis en_US
dc.title A tuberculin skin test survey among Ghanaian school children. en_US
dc.type Article en_US


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  • Bacteriology Department [105]
    The Bacteriology Department aims to improve the quality of life first for Ghanaians and the world at large by conducting research into bacterial diseases of public health importance to Ghana and globally. In addition to working on enteric pathogens and sexually transmitted diseases, the department’s current main focus is on the two most important mycobacterial diseases of public health importance to Ghana, namely Buruli ulcer (BU) and tuberculosis (TB).

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