Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men

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dc.contributor.author Kehinde, E.O.
dc.contributor.author Mojiminiyi, O.A.
dc.contributor.author Sheikh, M.
dc.contributor.author Al-Awadi, K.A.
dc.contributor.author Daar, A.S.
dc.contributor.author Al-Hunayan, A.
dc.contributor.author Anim, J.T.
dc.contributor.author Al-Sumait, A.A.
dc.date.accessioned 2013-06-25T19:50:29Z
dc.date.accessioned 2017-10-19T12:53:31Z
dc.date.available 2013-06-25T19:50:29Z
dc.date.available 2017-10-19T12:53:31Z
dc.date.issued 2005-08
dc.identifier.citation Kehinde, E. O., Mojiminiyi, O. A., Anim, J. T., Al-Awadi, K. A., Daar, A. S., Al-Hunayan, A., . . . Al-Sumait, A. A. (2005). Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men. BJU International, 96(3), 308-312. Link to full text: http://hinari-gw.who.int/whalecomlink.springer.com/whalecom0/article/10.1007%2Fs11255-005-4683-2 en_US
dc.identifier.issn 14644096
dc.identifier.uri http://197.255.68.203/handle/123456789/4129
dc.description.abstract OBJECTIVE: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men. SUBJECTS AND METHODS: Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15-79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age-specific ranges for PSA levels and prostate volume determined. RESULTS: The serum PSA ranges (ng/mL) for each age range in Arab men were: 40-49 years, 0-0.9; 60-69, 0-2.7; 70-79, 0-5.5 ng/mL; the respective prostate volumes were 8-22, 9-30 and 10-33 mL. The serum PSA level and prostate volume correlated with age (P < 0.001). Arab men had lower serum PSA levels and prostate volumes than those reported for Caucasians, but similar to those reported for Asians (Japanese and Chinese). CONCLUSION: These results indicate that Arab men have lower PSA levels and prostate volumes than Caucasians. The levels are slightly lower than those reported in the Japanese and, as in the Japanese, low PSA levels and small prostate volumes might be related to the low incidence of clinical prostate cancer in Arab men. en_US
dc.language.iso en en_US
dc.publisher BJU International en_US
dc.subject Arab en_US
dc.subject Asian en_US
dc.subject Caucasian en_US
dc.subject Prostate volume en_US
dc.subject Prostate-specific antigen en_US
dc.title Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men en_US
dc.type Article en_US


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