Effects of the Intake of Natural Cocoa Powder on Some Biochemical and Haematological Indices in the Rat

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dc.contributor.author Abrokwah, F.K.
dc.contributor.author Asamoah, K.A.
dc.contributor.author Esubonteng, P.K.A.
dc.date.accessioned 2019-10-09T16:56:02Z
dc.date.available 2019-10-09T16:56:02Z
dc.date.issued 2009-12
dc.identifier.uri http://www.ghanamedj.org/articles/December2009/Final%20intake%20of%20natural%20cocoa%20powder.pdf
dc.identifier.uri http://ugspace.ug.edu.gh/handle/123456789/32580
dc.description Journal Article en_US
dc.description.abstract Background: Natural cocoa and cocoa products are increasingly attracting the attention of many investigators and the general public because of their potential nutritional and medicinal properties and other claims. Objective: This study sought to evaluate the effect the consumption of natural cocoa powder has on some biochemical and hematological indices in the rat, as a way of establishing the biochemical basis for some of the claims made for the consumption of cocoa and its products. Methods: Male Wistar albino rats were fed natural cocoa powder in an aqueous suspension for 48 days, Biochemical and haematological indices were then determined from blood samples. Results: The treatment had no significant effect on ALT, AST, ALP, uric acid, total protein, haemoglobin and haematocrit levels. However, there were significant reductions in the total cholesterol level (2.52 ± 0.07 mmol/L) versus (1.88 ± 0.23 mmol/L), LDL – cholesterol level (1.09 ± 0.03 m mol/L) versus (0.74 ± 0.06 m mol/L), and in triglyceride level (1.28 ± 0.15 m mol/L) versus (1.08 ± 0.04 m mol/L) after treatment (p <0.05). The results further indicated significant increases in white blood cell (7.53 ± 0.19 × 103/mm3) versus (10.40 ± 1.66 × 103/mm3) and platelet counts (379± 112.0× 103/mm3) versus (583.8±11.4× 103/mm3). Conclusion: The administration of natural cocoa powder to rats caused significant reductions in total serum cholesterol levels, LDL-cholesterol levels and triglycerides with a significant increase in white blood cell counts. en_US
dc.language.iso en en_US
dc.publisher Ghana Medical Journal en_US
dc.relation.ispartofseries 43;4
dc.subject Cocoa powder en_US
dc.subject alanine aminotransferase en_US
dc.subject aspartate aminotransferase en_US
dc.subject alkaline phosphatase en_US
dc.subject lipid profile en_US
dc.title Effects of the Intake of Natural Cocoa Powder on Some Biochemical and Haematological Indices in the Rat en_US
dc.type Article en_US

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