Graphene nanoplatelet-based sensor for the detection of dopamine and N-acetyl-p-aminophenol in urine

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dc.contributor.author Krampa, F.D.
dc.contributor.author Aniweh, Y.
dc.contributor.author Kanyong, P.
dc.contributor.author Awandare, G.A.
dc.date.accessioned 2019-07-22T11:47:03Z
dc.date.available 2019-07-22T11:47:03Z
dc.date.issued 2018-10
dc.identifier.other https://doi.org/10.1016/j.arabjc.2018.10.006
dc.identifier.uri http://ugspace.ug.edu.gh/handle/123456789/31607
dc.description.abstract This paper reports the development and application of a disposable sensor for the individual and simultaneous voltammetric determination of dopamine (DA) and N-acetyl-p-aminophenol (APAP). The sensor was fabricated by drop-coating graphene nanoplatelets (GNPs)-Nafion (Naf) nanocomposite onto the working area of a screen-printed electrode (SPE). The sensor, designated as GNPs-Naf/SPE, was characterized by scanning electron microscopy (SEM), Raman spectroscopy, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). Differential pulse voltammetry (DPV) was used to simultaneously analyze DA and APAP in their binary mixtures. It showed excellent selectivity and sensitivity toward both compounds with limit of detection of 0.13 µM and 0.25 µM (S/N = 3) for DA and APAP, respectively. The performance of the sensor was evaluated by analyzing the compounds in human urine samples, and the recoveries were found to be well over 97.0%. en_US
dc.language.iso en en_US
dc.publisher Arabian Journal of Chemistry en_US
dc.subject Dual sensor en_US
dc.subject Nanocomposites en_US
dc.subject Modified electrodes en_US
dc.subject Simultaneous electrochemical analysis en_US
dc.title Graphene nanoplatelet-based sensor for the detection of dopamine and N-acetyl-p-aminophenol in urine en_US
dc.type Article en_US


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