Type-I HTLV antibody in urban and rural Ghana, West Africa.

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dc.contributor.author Biggar, R.J.
dc.contributor.author Saxinger, C.
dc.contributor.author Gardiner, C.
dc.contributor.author Collins, W.E.
dc.contributor.author Levine, P.H.
dc.contributor.author Clark, J.W.
dc.contributor.author Nkrumah, F.K.
dc.contributor.author Blattner, W.A.
dc.date.accessioned 2013-06-12T11:46:29Z
dc.date.accessioned 2017-10-16T12:58:02Z
dc.date.available 2013-06-12T11:46:29Z
dc.date.available 2017-10-16T12:58:02Z
dc.date.issued 1984
dc.identifier.citation Biggar, R. J., Saxinger, C., Gardiner, C., Collins, W. E., Levine, P. H., Clark, J. W., . . . Blattner, W. A. (1984). Type-I HTLV antibody in urban and rural Ghana, West Africa. International Journal of Cancer, 34(2), 215-219. en_US
dc.description.abstract The prevalence of antibodies against the newly described human T-cell lymphoma virus, type I (HTLV-I) in two communities in Ghana, West Africa, is described. There was no difference by community (urban, 3.6% and rural, 4.0%). Prevalence increased with age, being 5.9% among persons greater than 10 years old, but did not differ by sex. There was no difference when data were analysed by housing status or crowding. Non-confirmed reactions in the assay system were frequent and correlated with both prevalence and titer of antibody against malaria. Possible explanations include vector-borne transmission like that of malaria, but the relationship is more probably due to a polyclonal stimulation of B cells, enhancing the potential for detecting reactivity in the assay. Because assay systems vary and because most laboratories do not routinely use a confirmation assay, results presented by different groups must be interpreted cautiously. en_US
dc.language.iso en en_US
dc.publisher International Journal of Cancer en_US
dc.subject Adolescent en_US
dc.subject Adult en_US
dc.subject Age factors en_US
dc.subject Antibodies en_US
dc.subject Child en_US
dc.subject Child, preschool en_US
dc.subject Deltaretrovirus en_US
dc.subject Female en_US
dc.subject Ghana en_US
dc.subject Herpes virus 4 en_US
dc.subject Humans en_US
dc.subject Infant en_US
dc.subject Male en_US
dc.subject Plasmodium falciparum en_US
dc.subject Retroviridae infections en_US
dc.subject Rural population en_US
dc.subject Socio-economic factors en_US
dc.subject Urban population en_US
dc.title Type-I HTLV antibody in urban and rural Ghana, West Africa. en_US
dc.type Article en_US

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  • Virology Department [113]
    Most research activities involve the use of molecular methods such as regular PCR (PCR), quantitative PCR (Q-PCR), genomic sequence and analysis using different software, genetic engineering, probe hybridization techniques, biological and molecular cloning, evaluation of immune markers for laboratory diagnosis of infections, serological assays involving the use of rapid tests, ELISA-based evaluations and immunofluorescent assay techniques.

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