|Title:||Cardiopulmonary bypass in sickle cell anaemia without exchange transfusion|
|Keywords:||EMTREE medical terms: article; blood transfusion; cardiopulmonary bypass; case report; child; doppler echocardiography; exchange blood transfusion; female; hemoglobinopathy; hemolysis; human; hypothermia; male; mitral valve regurgitation; mitral valve replacement; priority journal; sickle cell anemia|
MeSH: Anemia, Sickle Cell; Cardiopulmonary Bypass; Child; Exchange Transfusion, Whole Blood; Female; Heart Valve Prosthesis Implantation; Humans; Intraoperative Care; Male; Mitral Valve Insufficiency
|Citation:||Frimpong-Boateng, K., Amoah, A. G. B., Barwasser, H. -., & Kallen, C. (1998). Cardiopulmonary bypass in sickle cell anaemia without exchange transfusion. European Journal of Cardio-Thoracic Surgery, 14(5), 527-529.|
|Abstract:||To minimize sickling during cardiopulmonary bypass, exchange transfusion is frequently recommended peri-operatively for patients with homozygous sickle cell anaemia to reduce the circulating concentration of HbS. We report the successful management of two children both aged 12 years with sickle cell anaemia (homozygous SS), several sickle cell crises and multiple blood transfusions who underwent cardiopulmonary bypass for mitral valve replacement. No pre- or intra-operative exchange transfusions were employed in the two cases. Furthermore, moderate hypothermia in both cases was not associated with adverse sequelae.|
|Appears in Collections:||Department of Anaesthetics 9|
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