Recent Advances in Astragalus membranaceus Anti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents

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dc.contributor.author Agyemang, K.
dc.contributor.author Han, L.
dc.contributor.author Liu, E.
dc.contributor.author Zhang, Y.
dc.contributor.author Wang, T.
dc.contributor.author Gao, X.
dc.date.accessioned 2018-08-10T09:13:51Z
dc.date.available 2018-08-10T09:13:51Z
dc.date.issued 2013-11-05
dc.identifier.uri http://ugspace.ug.edu.gh/handle/123456789/23846
dc.description Research Article en_US
dc.description.abstract The disease burden of diabetes mellitus is increasing throughout the world. The need for more potent drugs to complement the present anti-diabetic drugs has become an imperative. Astragalus membranaceus, a key component of most Chinese herbal antidiabetic formulas, has been an important prospect for lead anti-diabetic compounds. It has been progressively studied for its antidiabetic properties. Ethnopharmacological studies have established its potential to alleviate diabetes mellitus. Recent studies have sought to relate its chemical constituents to types 1 and 2 diabetes mellitus. Its total polysaccharides, saponins, and flavonoids fractions and several isolated compounds have been the most studied. The total polysaccharides fraction demonstrated activity to both types 1 and 2 diabetes mellitus.This paper discusses the anti-diabetic effects and pharmacological action of the chemical constituents in relation to types 1 and 2 diabetes mellitus. en_US
dc.language.iso en en_US
dc.publisher Hindawi Publishing Corporation, Evidence-Based Complementary and Alternative Medicine en_US
dc.relation.ispartofseries 2013;
dc.subject Astragalus membranaceus en_US
dc.subject Anti-Diabetic en_US
dc.subject Pharmacological Effects en_US
dc.subject Phytochemical Constituents en_US
dc.title Recent Advances in Astragalus membranaceus Anti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents en_US
dc.type Article en_US


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  • Clinical Pathology Department [34]
    The Clinical Pathology Department conducts research that contributes to intervention strategies and safeguards of public health in Ghana. In view of this the Department carries out research into plant medicine development, drug interactions and regulation, bio-monitoring and prevention of poisoning from environmental toxicants (e.g. mycotoxins specifically aflatoxins and toxic heavy metals). The Department also provides specialized laboratory services in support of public health programmes.

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