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Title: Current Practices in the Management of Lymphatic Filariasis
Authors: Bockarie, M.J.
Taylor, M.J.
Gyapong, J.O.
Keywords: Albendazole
lymphatic filariasis
mass drug administration
morbidity control
Neglected tropical disease
preventive chemotherapy
vector control
Issue Date: 2009
Publisher: Expert Reviews
Citation: Expert Rev. Anti Infect. Ther. 7(5), 595-605 (2009)
Abstract: Lymphatic Filariasis is a major cause of acute and chronic morbidity in 81 countries. The availability of safe treatment regimes along with rapid diagnostic tools resulted in a global program to eliminate the disease. The two main objectives of the global elimination program are to interrupt transmission of the parasites and to provide care for those with the disease. The strategy for transmission interruption is preventive chemotherapy through mass drug administration. This article reviews the current treatment regiments for lymphatic filariasis and discusses the challenges posed by co-endemicity with other diseases. The role of intergrated vector management as a supplementary strategy for mass drug administration and new strategies for treatment morbidity control through antibiotic targeting of the wolbachia endosymbionts are also discussed.
Appears in Collections:School of Public Health 9

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