Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1680
Title: Joint reviews and inspections: strategic forms of collaboration for strengthening the regulatory oversight of vaccine clinical trials in Africa
Authors: Maïga, D.
Akanmori, B.D.
Chocarro, L.
Issue Date: 2009
Publisher: Vaccine
Citation: Vaccine 28(2): 571-5
Abstract: Vaccine developers are required to submit a clinical trial application to the authorities in each country where a clinical trial will be conducted. The application has to be made both to the relevant Ethics Committees and to the National Regulatory Authorities, and only after appropriate clearance by both can a clinical trial commence. This paper describes two specific strategies, joint reviews of vaccine clinical trial applications and joint inspections of clinical trial sites by groups of countries, as part of a WHO initiative to strengthen capacity for the regulatory oversight of clinical trials in Africa. Significantly, the joint reviews and inspections contributed to reinforcing the capacities of the regulatory authorities as well as defining an efficient process to maximize the quality of the reviews and minimize undue delays. Finally we will suggest complementary mechanisms to overcome the potential limitations of joint reviews and inspections.
URI: http://hdl.handle.net/123456789/1680
Appears in Collections:Noguchi Memorial Institute for Medical Research

Files in This Item:
There are no files associated with this item.


Items in UGSpace are protected by copyright, with all rights reserved, unless otherwise indicated.